Studies with Mouse Pituitary Thyrotropic Tumors Ix. Distribution of Amino Acids under the Influence of Thyroxine1
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چکیده
tumors following radiothyroidectomy in mice. Later, Furth et at. (8) discovered that such tumors were capable of secreting thyrotropin and isolated from them both de pendent and autonomous strains, responsive and non responsive to thyroxine. Detailed studies have been made in this laboratory (10, 11, 14—16) with 3 strains of thyrotropic tumor obtained from Dr. Furth. Growth of 1 strain, dependent responsive, 4183, is suppressed by the administration of thyroid hormone to the host. Tumor cell implants of this strain can be suppressed by thyroxine
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Studies with Mouse Pituitary Thyrotropic Tumors. Ix. Distribution of Amino Acids under the Influence of Thyroxine.
tumors following radiothyroidectomy in mice. Later, Furth et at. (8) discovered that such tumors were capable of secreting thyrotropin and isolated from them both de pendent and autonomous strains, responsive and non responsive to thyroxine. Detailed studies have been made in this laboratory (10, 11, 14—16) with 3 strains of thyrotropic tumor obtained from Dr. Furth. Growth of 1 strain, depen...
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A number of thyroxine derivatives have been studied for effects on growth and secretory ac tivity of mouse pituitary thyrotropic tumors. Three tumors, dependent-responsive (4183), auton omous responsive (L24), and autonomous nonresponsive (L23), were employed. No unique abil ity to suppress tumor growth was demonstrated, and most of the analogs were found to be inactive. Augmentation in growth ...
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